G.J. Ramakers, D. Wolfer, G. Rosenberger, K. Kuchenbecker, H.-J. Kreienkamp, J. Prange-Kiel, G. Rune, K. Richter, K. Langnaese, S. Masneuf, M.R. Bösl, K.D. Fischer, H.J. Krugers, H.P. Lipp, E. van Galen, K. Kutsche
Dysregulation of Rho GTPases in the ?Pix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits.
Hum. Mol. Genet., 21(2), 268-86 (2012)PM
F. Kortüm, M. Chyrek, S. Fuchs, B. Albrecht, G. Gillessen-Kaesbach, U. Mütze, E. Seemanova, S. Tinschert, D. Wieczorek, G. Rosenberger, K. Kutsche
Hallermann-Streiff Syndrome: No Evidence for a Link to Laminopathies.
Mol Syndromol, 2(1), 27-34 (2011)PM
K.T. Hua, C.T. Tan, G. Johansson, J.M. Lee, P.W. Yang, H.Y. Lu, C.K. Chen, J.L. Su, P.B. Chen, Y.L. Wu, C.C. Chi, H.J. Kao, H.J. Shih, M.W. Chen, M.H. Chien, P.S. Chen, W.J. Lee, T.Y. Cheng, G. Rosenberger, C.Y. Chai, C.J. Yang, M.S. Huang, T.C. Lai, T.Y. Chou, M. Hsiao, M.L. Kuo
N-?-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity.
Cancer Cell, 19(2), 218-31 (2011)PM
S. Endele, G. Rosenberger, K. Geider, B. Popp, C. Tamer, I. Stefanova, M. Milh, F. Kortüm, A. Fritsch, F.K. Pientka, Y. Hellenbroich, V.M. Kalscheuer, J. Kohlhase, U. Moog, G. Rappold, A. Rauch, H.H. Ropers, S. von Spiczak, H. Tönnies, N. Villeneuve, L. Villard, B. Zabel, M. Zenker, B. Laube, A. Reis, D. Wieczorek, L. Van Maldergem, K. Kutsche
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.
Nat. Genet., 42(11), 1021-6 (2010)PM
H.G. Kim, J.W. Ahn, I. Kurth, R. Ullmann, H.T. Kim, A. Kulharya, K.S. Ha, Y. Itokawa, I. Meliciani, W. Wenzel, D. Lee, G. Rosenberger, M. Ozata, D.P. Bick, R.J. Sherins, T. Nagase, M. Tekin, S.H. Kim, C.H. Kim, H.H. Ropers, J.F. Gusella, V. Kalscheuer, C.Y. Choi, L.C. Layman
WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome.
Am. J. Hum. Genet., 87(4), 465-79 (2010)PM
L. Gremer, A. De Luca, T. Merbitz-Zahradnik, B. Dallapiccola, S. Morlot, M. Tartaglia, K. Kutsche, M.R. Ahmadian, G. Rosenberger
Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation.
Hum. Mol. Genet., 19(5), 790-802 (2010)PM
G. Rosenberger, S. Meien, K. Kutsche
Oncogenic HRAS mutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome.
Hum. Mutat., 30(3), 352-62 (2009)PM
H.G. Kim, I. Kurth, F. Lan, I. Meliciani, W. Wenzel, S.H. Eom, G.B. Kang, G. Rosenberger, M. Tekin, M. Ozata, D.P. Bick, R.J. Sherins, S.L. Walker, Y. Shi, J.F. Gusella, L.C. Layman
Mutations in CHD7, encoding a chromatin-remodeling protein, cause idiopathic hypogonadotropic hypogonadism and Kallmann syndrome.
Am. J. Hum. Genet., 83(4), 511-9 (2008)PM
A. Gringel, D. Walz, G. Rosenberger, A. Minden, K. Kutsche, P. Kopp, S. Linder
PAK4 and alphaPIX determine podosome size and number in macrophages through localized actin regulation.
J. Cell. Physiol., 209(2), 568-79 (2006)PM
I. Wimplinger, M. Morleo, G. Rosenberger, D. Iaconis, U. Orth, P. Meinecke, I. Lerer, A. Ballabio, A. Gal, B. Franco, K. Kutsche
Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin defects syndrome.
Am. J. Hum. Genet., 79(5), 878-89 (2006)PM
G. Rosenberger, K. Kutsche
AlphaPIX and betaPIX and their role in focal adhesion formation.
Eur. J. Cell Biol., 85(3-4), 265-74 (2006)ReviewPM
C. Hartwig, A. Veske, S. Krejcova, G. Rosenberger, U. Finckh
Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin.
BMC Neurosci, 6, 53 (2005)PM
G. Rosenberger, A. Gal, K. Kutsche
AlphaPIX associates with calpain 4, the small subunit of calpain, and has a dual role in integrin-mediated cell spreading.
J. Biol. Chem., 280(8), 6879-89 (2005)PM
C. Leisser, G. Rosenberger, S. Maier, G. Fuhrmann, M. Grusch, S. Strasser, S. Huettenbrenner, S. Fassl, D. Polgar, S. Krieger, C. Cerni, R. Hofer-Warbinek, R. deMartin, G. Krupitza
Subcellular localisation of Cdc25A determines cell fate.
Cell Death Differ., 11(1), 80-9 (2004)PM
S. Fassl, C. Leisser, S. Huettenbrenner, S. Maier, G. Rosenberger, S. Strasser, M. Grusch, G. Fuhrmann, K. Leuhuber, D. Polgar, J. Stani, B. Tichy, C. Nowotny, G. Krupitza
Transferrin ensures survival of ovarian carcinoma cells when apoptosis is induced by TNFalpha, FasL, TRAIL, or Myc.
Oncogene, 22(51), 8343-55 (2003)PM
G. Rosenberger, I. Jantke, A. Gal, K. Kutsche
Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling.
Hum. Mol. Genet., 12(2), 155-67 (2003)PM
G. Fuhrmann, C. Leisser, G. Rosenberger, M. Grusch, S. Huettenbrenner, T. Halama, I. Mosberger, S. Sasgary, C. Cerni, G. Krupitza
Cdc25A phosphatase suppresses apoptosis induced by serum deprivation.
Oncogene, 20(33), 4542-53 (2001)PM
M. Grusch, M. Fritzer-Szekeres, G. Fuhrmann, G. Rosenberger, C. Luxbacher, H.L. Elford, K. Smid, G.J. Peters, T. Szekeres, G. Krupitza
Activation of caspases and induction of apoptosis by novel ribonucleotide reductase inhibitors amidox and didox.
Exp. Hematol., 29(5), 623-32 (2001)PM
G. Rosenberger, G. Fuhrmann, M. Grusch, S. Fassl, H.L. Elford, K. Smid, G.J. Peters, T. Szekeres, G. Krupitza
The ribonucleotide reductase inhibitor trimidox induces c-myc and apoptosis of human ovarian carcinoma cells.
Life Sci., 67(26), 3131-42 (2000)PM
